Avinash Kale - Actin Polymerization In Apicomplexan: A Structural, Functional And Evolutionary Analysis

Actin Polymerization In Apicomplexan: A Structural, Functional And Evolutionary Analysis por Avinash Kale epub

Descargar Actin Polymerization In Apicomplexan: A Structural, Functional And Evolutionary Analysis por Avinash Kale Epub y PDF

  • Título: Actin Polymerization In Apicomplexan: A Structural, Functional And Evolutionary Analysis
  • Autores: Avinash Kale
  • Publicado: 1 de diciembre de 2019
  • ISBN: 981137449X
  • Tamaño: .MB
  • Nº de páginas: 147
  • Idiomas: Español
  • Editorial: www.thwfx.com.mx
  • Valoración: ★★★★★
  • País: España
  • Genero: Novela kindle
  • Comprimido: no
  • Formato : PDF, EPUB

Avinash Kale con Actin Polymerization In Apicomplexan: A Structural, Functional And Evolutionary Analysis

This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements. The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13–24 as potential drug targets against malaria.  As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design. Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.
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